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\n Director, Sustainability Macclesfield, UK (3 days on site per week) About AstraZeneca\n AstraZeneca is a global, science‑led, patient‑focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death. Come and join our AZ team where you will play a pivotal role in this exciting period of development!!\n The Director Sustainability leads a matrix team by fostering a collaborative, knowledge‑sharing environment, empowering team members, and driving accountability for sustainability initiatives. This role spearheads the Chemical Development sustainability initiative and actively collaborates to align with AstraZeneca’s overall sustainability ambition. By leveraging the diverse expertise of the team and fostering cross‑functional cooperation, this leadership approach ensures agility, proactivity, and a steadfast commitment to achieving long‑term sustainable outcomes. Key Responsibilities:\n \n • \n Strategic Leadership: Develop and lead the execution of a comprehensive sustainability strategy for the Chemical Development Department, ensuring alignment with broader corporate sustainability objectives and positioning the department as an industry leader in green chemistry. Provide strategic insights, data, and recommendations to senior leadership on sustainability matters, helping to influence decision‑making and future investments in sustainable development. \n • \n Team Leadership: Guide cross‑functional teams, ensuring that sustainability principles are embedded in every stage of process development (from development through to commercialisation) and in department operations. Cultivate a culture of continuous improvement and innovation within the internal team. \n • \n Advisory Role for External Partners: Serve as the key sustainability advisor for CDMO partners, driving the adoption of green chemistry, sustainable practices and carbon footprint reduction throughout the supply chain and manufacturing processes. Ensure that external partners share our sustainability goals and regulatory requirements. \n • \n Sustainable Innovation: Through the team, identify and champion innovative technologies and processes that improve environmental sustainability, reduce waste, and minimise resource consumption. Ensure that innovations are aligned with long‑term business and environmental objectives. \n • \n Regulatory and Compliance Oversight: Working with global SHE and ESM, ensure that all external partnerships align with relevant environmental regulations and sustainability standards. Work closely with regulatory teams to anticipate and adapt to evolving environmental policies. \n • \n Collaboration and Influence: Build strong relationships with internal departments (R&D, Manufacturing, Supply Chain) and external stakeholders to ensure a seamless approach to sustainability across all operations. Promote internal awareness and engagement through education and advocacy at all levels. \n Requirements:\n \n • \n A degree in chemistry, chemical engineering, pharmaceutical sciences, or a related subject area, alongside significant relevant experience in pharmaceutical, chemical, or manufacturing environments. \n • \n Proven experience in developing and implementing sustainability strategies, ideally within chemical development, process chemistry, manufacturing, or supply chain operations. \n • \n Detailed understanding of environmental compliance, sustainability standards, and evolving regulatory expectations relevant to the pharmaceutical sector. \n • \n Excellent communication, stakeholder engagement, and influencing skills, including experience presenting recommendations to senior leadership. \n • \n Significant experience working within a Research & Development or Manufacturing environments, within the pharmaceutical industry with comprehensive knowledge of development. \n • \n Clear understanding of the full drug development pathway and how chemical development contributes to this. \n • \n Strong technical expertise and understanding of practical synthetic organic chemistry and process development. \n • \n Detailed understanding of the overall drug development process from discovery through to launch and lifecycle management. \n • \n Strong external profile demonstrating scientific leadership. \n • \n Extensive knowledge and experience of the subject areas within chemical development and how they combine to deliver commercial manufacturing processes and control strategies. \n In Office Requirement:\n When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Competitive salary and benefits package on offer!\n The successful candidate will have access to a flexible employee benefits fund, including holiday purchase and flexible time off, pension contributions, Share Save Plans, a performance recognition scheme and a competitive, generous remuneration package. \n Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. \n #J-18808-Ljbffr

AstraZeneca Macclesfield seeks a Director of Sustainability to lead a matrix team and drive a comprehensive sustainability strategy for the Chemical Development Department, aligning with broader corporate goals. You will shape external partnerships, advance green chemistry, ensure regulatory compliance, and foster collaboration with R&D, Manufacturing, and Supply Chain to deliver sustainable outcomes. #J-18808-Ljbffr

AstraZeneca is seeking a senior leader to guide construction health and safety for a multinational capital program in manufacturing and R&D facilities. You will set strategy, embed Safe-by-Design, and partner across engineering, SHE, procurement and site leadership to protect people and ensure project continuity. You will lead global standards, governance and assurance programmes, drive incident investigations and continuous improvement, and develop a high-performing construction safety team #J-18808-Ljbffr

Are you ready to set the global standard for construction safety that safeguards individuals and keeps life‑changing medicines moving? This is a chance to shape how we build the next generation of advanced manufacturing and R&D facilities that bring therapies to patients faster and more reliably. AstraZeneca has a large and exciting portfolio of capital investments across our manufacturing network and our Global Engineering team is leading the delivery of these projects. Working with the Head of Capital Projects, you will lead construction health and safety strategy and performance across a diverse, multinational capital portfolio. You will partner with Global Engineering Project Delivery teams, Global Operations Safety Health and Environment (SHE), Procurement, Site Leadership and our design and construction partners to embed safe‑by‑design thinking and provide construction SHE leadership from concept through handover. You will create the framework, capability and culture that enable our projects to deliver safely, compliantly and at pace—so patients receive the medicines they need without disruption. • Strategy and Governance: Lead the global construction health and safety strategy across the capital portfolio, aligning with corporate Safety, Health & Environment expectations and business objectives to protect people and ensure continuity., • Standards and Critical Risk Control: Develop and maintain global standards for high‑risk work, contractor management, assurance and incident management; drive consistent control of activities such as work at height, lifting operations, excavation, electrical safety, temporary works, confined space entry, hot work, traffic management and permit‑to‑work., • Safe‑by‑Design Integration: Partner with engineering and project teams to eliminate or reduce risk early through concept and design decisions, planning and procurement., • Contractor Safety Excellence: Set clear expectations for prequalification, selection support, onboarding, performance monitoring and intervention; improve on contractor safety performance worldwide., • Assurance and Continuous Improvement: Lead or oversee audits, inspections, maturity assessments and management reviews; use leading and lagging indicators, trends and lessons learned to improve controls and outcomes., • Incident Response and Learning: Provide timely, calm and measured escalation for incidents that happen. If necessary, provide support and guidance for project teams dealing with incidents. Lead serious incident reviews and investigations to root cause; ensure corrective actions are effective and learning is shared across regions and projects., • Leadership and Influence: Coach senior leaders and project teams to demonstrate visible safety leadership, make risk‑based decisions and own construction safety outcomes., • Capability and Team Development: Recruit, develop and deploy a diverse group of construction safety professionals; define capability needs, build succession and enable consistent ways of working., • Regulatory Compliance and Pragmatic Risk Management: Ensure compliance across jurisdictions while maintaining a globally consistent, risk‑based approach that works in the field., • Portfolio Oversight and Issue Management: Represent construction safety in governance forums and project evaluations; provide clear recommendations and raise concerns when standards are not met., • Emergency Preparedness: Contribute to planning and response for major construction projects and significant events., • Degree or equivalent experience in Occupational Health and Safety, Construction Management, Environmental Health and Safety, Engineering, or a related field., • A recognised advanced health and safety qualification such as NEBOSH International Diploma or equivalent international certification., • Significant experience in construction health and safety leadership, typically gained over 10 or more years, within large, complex, and multinational project environments., • Demonstrated success leading health and safety across major capital projects in sectors such as pharmaceuticals, life sciences, advanced manufacturing, industrial, process, or similarly regulated and high‑hazard environments., • Strong experience in contractor health and safety management, including prequalification, mobilisation, governance, performance management, and assurance., • Deep practical knowledge of high‑risk construction activities and critical control management, including work at height, lifting operations, excavation, electrical safety, temporary works, confined space entry, and permit‑to‑work systems., • Experience in developing and implementing global standards, governance frameworks, and assurance programmes for construction safety., • Demonstrated capability in incident investigation, root cause analysis, audit and inspection, and corrective action management., • Experience working in a highly regulated environment where quality, compliance, and operational continuity are critical., • Strong experience engaging and influencing senior leaders, project directors, engineering leaders, site leadership teams, procurement, and external contractors., • Experience recruiting, leading, and developing multidisciplinary or geographically dispersed health and safety teams, with the ability to build capability and align resources to business and project priorities., • Chartered, certified, or equivalent professional accreditation with a recognised professional body, such as Chartered Member IOSH, Certified Safety Professional, Senior Certified Safety Engineer, ChOHSP or equivalents that demonstrate comparable technical depth, professional credibility, and relevance to construction health and safety leadership., • Additional training or certification in areas such as ISO 45001 auditing, process safety, human and organisational performance, behavioural safety., • Experience within a global pharmaceutical, biopharmaceutical, or life sciences organisation., • Experience supporting projects across the full lifecycle, from concept and design through construction, commissioning, qualification, and operational handover., • Experience in owner‑side construction governance within a large corporate environment, in addition to any contractor‑side background., • Experience working across multiple regions and jurisdictions, including EMEA, US, APAC, and other international settings., • Familiarity with integrating construction health and safety with broader EHS, quality, engineering, and operational excellence frameworks., • Experience contributing to sustainability, wellbeing, and broader ESG‑related considerations in project delivery., • Experience building or leading a global construction safety function or centre of expertise, including organisational design, talent development, and capability building across a capital project portfolio. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Here you will help turn scientific breakthroughs into facilities and systems that deliver medicines at speed and scale, working with innovative design, digital tools and lean methods to remove risk before it reaches the site. You will collaborate across borders with specialists in engineering, science and delivery who value kindness alongside ambition, and who rally around a clear purpose to improve patients’ lives while advancing sustainability. Expect global scope, the chance to build a lasting safety capability, and the empowerment to make high‑consequence decisions that keep our people safe and our supply reliable. Step in to lead a global safety agenda that protects people and accelerates how the world’s medicines are built—make your impact today! Date Posted: 13-Jul-2026 Closing Date: 26-Jul-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. #J-18808-Ljbffr

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