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\n About ScionxBio\n ScionxBio is engineering the next generation of RNA medicines, combining synthetic chemistry and artificial intelligence to create xRNA — a platform for long‑acting therapeutics. By expanding RNA beyond nature's four‑letter alphabet, we engineer molecules that sustain protein expression for weeks to months rather than days, with a lower immunogenic burden and the durability that chronic disease demands. At the heart of the platform is our TERA® engine, a closed‑loop system in which deep‑learning design, proprietary combinatorial assembly, high‑throughput screening, and continuous model retraining work together to optimise each molecule for its payload. With an initial focus on cardiometabolic disease, we are working to turn transient treatments into durable therapies. A spin‑out from Eleven Therapeutics, we are an international team operating across Cambridge (UK), Tel Aviv, and Cambridge (MA), with our Cambridge (UK) site serving as our largest research and development hub. Role Overview\n The Vice President of Platform is the architect of ScionxBio's core technology engine. Reporting to the CEO and sitting within the company's senior leadership, this individual owns the entire upstream pipeline — from computational design and AI‑driven sequence optimisation through to the formulation and delivery systems that carry our molecules into the body, and onward into the evolution of our next‑generation xRNA modalities. This is a rare opportunity to lead, and continue to build, the platform that defines the company: to set its scientific direction, to shape a multidisciplinary team of exceptional scientists and engineers, and to translate a validated modality into a durable, defensible, and endlessly generative source of medicines. We are looking for a scientific leader who is equally comfortable setting long‑range strategy and engaging deeply with the technical substance of the work. Core Responsibilities\n \n • Computational Biology and AI Innovation\n Lead the development of our proprietary AI/ML models and computational biology pipelines for sequence design, structural prediction, and codon optimisation, with the goal of maximising translation, stability, and tissue specificity. This work is conducted in close collaboration with our strategic advisor. \n • Next‑Generation xRNA Evolution\n Spearhead the continued strategic evolution of our modality, guiding the platform's advance into ever more sophisticated xRNA chemistries and ensuring that it remains firmly at the state of the art. \n • Formulation and LNP Development\n Oversee the formulation engineering team in optimising lipid nanoparticles (LNPs) for targeted, safe, and efficient in vivo delivery, again working in collaboration with our strategic advisor. \n • Platform Scalability\n Ensure that platform discoveries are robust, reproducible, and engineered from the outset with manufacturing scalability in mind, so that what works at the bench translates reliably towards the clinic. \n • Strategic Leadership\n Own the resourcing, planning, and timelines for the platform team, and mentor and grow a multidisciplinary group of data scientists, biologists, and engineers into a high‑performing, collaborative whole. \n • Intellectual Property Generation\n Actively identify and protect novel sequence motifs, AI design algorithms, and proprietary LNP formulations, building and defending the intellectual property moat that underpins the company's long‑term value. \n • Platform Interfacing\n Serve as the pivotal bridge between Platform and Discovery, working closely with our chemistry and biology colleagues to transition optimised candidates smoothly from the Platform team into the Discovery team. \n Qualifications and Experience\n \n • A PhD in a relevant discipline — for example computational biology, bioinformatics, RNA biology, biochemistry, chemical or biomedical engineering, or a closely related field — together with substantial and progressive experience in RNA, oligonucleotide, or nucleic‑acid therapeutics, gained over a senior industry career.\n, • A demonstrable track record of building and leading platform or technology functions in a biotech or pharmaceutical setting, including direct leadership of multidisciplinary teams spanning computation, biology, and engineering.\n, • Deep, hands‑on familiarity with the application of AI and machine learning to molecular design, together with a genuine understanding of the experimental science the platform serves.\n, • Strong knowledge of delivery technologies, in particular LNP formulation for nucleic acids, and of the considerations that carry a discovery‑stage platform towards manufacturable, scalable processes.\n, • A record of intellectual property generation, and the strategic instinct to recognise and protect what is defensible.\n, • Outstanding leadership, communication, and collaboration skills, with the ability to operate effectively across a geographically distributed, multicultural organisation and to translate between technical and strategic audiences.\n What We Offer\n The opportunity to own and shape the defining technology platform of an ambitious, well‑founded biotech at a pivotal moment in its story; a seat within the senior leadership team, with real influence over the company's scientific direction; and the chance to build something durable alongside a talented, international community at the heart of the Cambridge life sciences ecosystem. \n #J-18808-Ljbffr

• Hampshire, UK, • Band 6 or 7, • Min. 18 hrs/week, • Up to £40/hr Are you an experienced Paediatric Occupational Therapist looking for flexible, long-term work in Hampshire? Were recruiting for a self-employed Associate/Locum OT to support children and young adults aged 2-25 across both public and private sectors. Role Highlights • Flexible hours: Minimum 18 hours/week up to full-time, • Hourly rate: £36 - £40 (based on experience and location), • Travel time and mileage paid for client visits, • Home working available for admin and report writing, • Supervision provided and paid, • Outside IR35 Key Responsibilities • Conduct assessments and deliver treatment sessions in homes, schools, nurseries, colleges, or clinics, • Manage own caseload and diary, • Write clinical notes and reports Requirements • HCPC & RCOT registered (with Professional Indemnity Insurance), • Minimum 2 years paediatric experience in specialist/community settings, • Sensory Integration qualifications (advantageous), • Full UK driving licence and own car, • Based in Hampshire, • Right to work in the UK (no sponsorship available), • Own laptop and mobile phone, • Enhanced DBS required Additional Info • Travel to clinic not paid (can be claimed on personal tax return), • Paid for confirmed cancellations (with 72 hrs notice) Interested in making a meaningful impact while maintaining flexibility? Apply now to learn more about this opportunity.

Heim is recruiting for a freelance phlebotomist specifically in Aberdeen, Inverness and the Highlands. You will be joining a group of existing phlebotomists, providing high-quality care to our clients and liaising with our Clinical Operations Team as required to report on activities. This role requires you to be able to travel and have your own car, as the vast majority of our appointments are delivered in the community (usually within the patient's home). The role is suitable for an experienced Phlebotomist (at least six months full-time) who wants to work flexibly. By joining Heim, you will have access to the best tools to support you as a freelance phlebotomist and the flexibility to work at hours and schedules that suit your “work life balance”. Heim's technology will let you communicate effectively and seamlessly with patients, log task completion, manage cancellations and seek support live. To be successful in this role, you will need to have a strong track record in providing excellent phlebotomy services for at least six months. Be part of the innovative service in home healthcare testing by joining Heim. You will be someone who is reliable, friendly, honest and able to maximize customer experience. At Heim, we value our staff and will offer successful candidates: • Flexibility and competitive pay rate, • Weekly pay, • Regular clinical and managerial supervision and support, • A programme of in-service training and exciting development opportunities, • Opportunity for service development and audit, • Agile working devices to support community and clinic based working, • Experience: Minimum 6 months phlebotomy experience, • DBS Disclosure of convictions (enhanced, child and adult), • Insurance: Personal professional indemnity insurance (evidence required), • References: 2 referees, at least one from your recent employment, • Driving License: Full driving license and access to own vehicle, • Language: Fluent English (required) Main Duties & Responsibilities Clinical duties: • To carry out blood tests requested and booked domiciliary visits, as a lone practitioner with telephone and mobile app support., • To seek advice and support from a more senior/experienced colleague / Heim Clinical team for matters outside the sphere of responsibility, knowledge, or skills., • To ensure that domiciliary blood samples are posted or brought to the hub in time for the courier collection., • To document into the patient’s medical record of blood tests taken., • Report to the Heim Clinical team and seek advice on specific risks that are identified, e.g. unsafe environmental conditions., • To carry out your duties in accordance with company protocols and guidelines. Requirements: • Adhere to company policies and procedures at all times., • Be comfortable working with a digital mobile tool to coordinate job assignments and record patient notes., • Take reasonable steps to manage and promote a safe and healthy working environment., • Respect the confidentiality and privacy of patients and carers at all times., • Maintain a constant awareness of health, welfare, and safety issues affecting colleagues, patients, relatives, and self and report incidents or near-miss events to the Clinical Operations Manager., • To function as an integral part of the phlebotomy team., • Attend relevant meetings as required., • Have working knowledge and an understanding of relevant legislations/policies e.g. Equal Opportunities, Health and safety and confidentiality., • Maintain compliance with all relevant training and participate in development and appraisal., • This is not an exhaustive list of duties, and the post holder may be required to undertake any other duties as required, to meet the needs of the service, so long as they do not exceed the level of responsibility expected for this grade.

Heim is recruiting for a freelance phlebotomist in Carlisle, Cumbria. You will be joining a group of existing phlebotomists, providing high-quality care to our clients and liaising with our Clinical Operations Team as required to report on activities. This role requires you to be able to travel and have your own car, as the vast majority of our appointments are delivered in the community (usually within the patient's home). The role is suitable for an experienced Phlebotomist (at least six months full-time) who wants to work flexibly. By joining Heim, you will have access to the best tools to support you as a freelance phlebotomist and the flexibility to work at hours and schedules that suit your “work life balance”. Heim's technology will let you communicate effectively and seamlessly with patients, log task completion, manage cancellations and seek support live. To be successful in this role, you will need to have a strong track record in providing excellent phlebotomy services for at least six months. Be part of the innovative service in home healthcare testing by joining Heim. You will be someone who is reliable, friendly, honest and able to maximize customer experience. At Heim, we value our staff and will offer successful candidates: • Flexibility and competitive pay rate, • Weekly pay, • Regular clinical and managerial supervision and support, • A programme of in-service training and exciting development opportunities, • Opportunity for service development and audit, • Agile working devices to support community and clinic based working, • Experience: Minimum 6 months phlebotomy experience, • DBS Disclosure of convictions (enhanced, child and adult), • Insurance: Personal professional indemnity insurance (evidence required), • References: 2 referees, at least one from your recent employment, • Driving License: Full driving license and access to own vehicle, • Language: Fluent English (required) Main Duties & Responsibilities Clinical duties: • To carry out blood tests requested and booked domiciliary visits, as a lone practitioner with telephone and mobile app support., • To seek advice and support from a more senior/experienced colleague / Heim Clinical team for matters outside the sphere of responsibility, knowledge, or skills., • To ensure that domiciliary blood samples are posted or brought to the hub in time for the courier collection., • To document into the patient’s medical record of blood tests taken., • Report to the Heim Clinical team and seek advice on specific risks that are identified, e.g. unsafe environmental conditions., • To carry out your duties in accordance with company protocols and guidelines. Requirements: • Adhere to company policies and procedures at all times., • Be comfortable working with a digital mobile tool to coordinate job assignments and record patient notes., • Take reasonable steps to manage and promote a safe and healthy working environment., • Respect the confidentiality and privacy of patients and carers at all times., • Maintain a constant awareness of health, welfare, and safety issues affecting colleagues, patients, relatives, and self and report incidents or near-miss events to the Clinical Operations Manager., • To function as an integral part of the phlebotomy team., • Attend relevant meetings as required., • Have working knowledge and an understanding of relevant legislations/policies e.g. Equal Opportunities, Health and safety and confidentiality., • Maintain compliance with all relevant training and participate in development and appraisal., • This is not an exhaustive list of duties, and the post holder may be required to undertake any other duties as required, to meet the needs of the service, so long as they do not exceed the level of responsibility expected for this grade.

We are looking for an exceptionally organised and proactive Medical Secretary to join our team at Fortius Clinic. In this vital role, you will provide high‑quality administrative support to ensure the smooth, efficient running of our medical office. You’ll be responsible for managing a variety of tasks in a fast‑paced environment, using your attention to detail, communication skills, and ability to multitask under pressure. As a key member of our patient‑focused team, you will help uphold the Fortius values of Making It Happen, Personalised Care, and Stronger Together. If you thrive in a collaborative setting, take pride in delivering outstanding service, and enjoy supporting both clinicians and patients with professionalism and warmth, we’d love to hear from you. • Provide comprehensive secretarial support and coordination of all administrative duties for designated consultants., • Manage consultant schedules, including booking outpatient and theatre appointments, and accurately recording annual leave, study leave, meetings, and other commitments., • Make amendments or cancellations to clinic lists as required, communicating effectively with internal teams to ensure appointments are appropriately rescheduled and reissued., • Complete imaging request forms within Meddbase, arrange appointments, and provide fee information to self‑funded patients., • Prepare consultant clinics in advance, ensuring all relevant documentation—such as imaging reports and referral letters—is received and ready prior to each patient appointment., • Organise theatre bookings, including completing booking forms, scheduling patients through Meddbase, sending and saving confirmations, and coordinating pre‑assessment and post‑operative appointments., • Liaise closely with internal departments (e.g., Radiology, Bookings, Appointments) to maintain a seamless and positive patient journey., • Review dictations, edit, and distribute clinic letters to patients, referrers, GPs, and other relevant parties., • Scan and upload medical documents and correspondence to the patient record accurately and promptly. Essential Previous experience in a similar role ideally - spine Strong verbal and written communication skills Excellent IT skills Strong organisational skills and ability to manage time effectively Professional, confident, and friendly manner Ability to work independently as well as part of a team Desirable Experience working in spine Significant understanding of medical terminology Our benefits are driven by what matters to our people. It’s important to us that these benefits support a work-life balance that keeps people healthy, both mentally and physically. As a Medical Secretary you’ll be eligible for: Benefits: Highly competitive salary Private Medical Insurance Company pension scheme Perkbox - save money while you shop! Employee Assistance Programme Occupational health services Season ticket loans Cycle to work scheme Childcare vouchers Your application has been successfully submitted! _

Hey! Shun here, I’m the CEO and co-founder of Anima. We’re building an active learning OS for all of healthcare and life sciences towards maximising human wellbeing globally. My entire life, I’ve been pulling on a thread that’s affected all of us in some way. Millions die every year because their medical problems aren’t treated quickly enough. Hundreds of millions suffer pain, worry and discomfort needlessly because of long waiting times. I trained as a doctor and quit out of frustration at seeing countless cases of people dying because they got misdiagnosed or didn’t get the right care plan. In one devastating incident, the healthcare system had simply forgotten to follow up about abnormal test results. Pulling the thread led me to the health spending team at HM Treasury, responsible for deploying 100s billions into the NHS - there, I worked on workforce and system reform policy with No.10 and NHS England (most notably on forming statutory ‘integrated care systems’, which was signed into law as part of the Health and Social Care Act). Seeing the problem space at all abstraction levels convinced me that the only way to fix healthcare was to build a ‘Care Enablement’ platform that can automate and abstract away work at the clinic, and 10x doctors. Doing so would also be the path to a superhuman personalised medicine agent that could go well beyond humans, crunching tens of thousands of low level features at genome and transcriptome level. At Anima, you’ll help us extend the 3 existing product lines we have, that millions of patients use, and build out new ones at the very cutting edge of healthcare reinforcement learning and agentic AI. Your work will save countless lives. I won’t write too much here, because I think the metrics speak for themselves and if we get further along the process, we can always discuss it more. Users love our product. The biggest testament to this is that most of our growth comes from virality and referrals. As one of the standout companies in YC’s W21 batch, we raised $2.5M before Demo Day in just 4 days, led by Hummingbird. In early 2024, we closed an oversubscribed Series A round of $12M, led by Molten Ventures. We’ve been turning down pre-emptive offers of more capital since 2024. Anima clinics look after 3 million lives, and every day around 20,000 people get care through Anima, growing fast. Since the beginning, we’ve cultivated a unique hacker culture at Anima with a flat hierarchy. If you look at some of our LinkedIn profiles, you’ll note that the title is often ‘Product at Anima’, which is a more accurate description of what your role will be - it’s much broader than the typical SWE role. We predict that small, killer T-shaped teams will win out over large mediocre ones in the era of agentic AI. We've been purposefully building a 'knights of the round table' where each person has an incredible amount of ownership, autonomy and human impact on saving lives - zero line managers, PMs or EMs, but an intensive focus on coaching and teaching. [In case you’ve seen the show, the best analogy is Firefly and the crew from it. Greatest show ever imo.] It started with me. I self taught and wrote a lot of the Anima 1.0 code, and Anima’s active learning patent. I run most of the hiring tech chats to this day. I first and foremost see myself as an IC and builder, and still build stuff in my spare time. More than 80% of our product team are VPs, ex-technical founders and former CTOs (we do not have titles internally). We also have domain experts, including full-stack clinical engineers: ex-MDs who left established medical careers to join Anima because they recognised the much higher leverage they’d have here. Almost everyone in Anima is at least somewhat technical and very UX focused. This makes for a truly flat hierarchy. Internally, people have described it as a hive mind - there is little semantic error because we all deeply understand the problem, engineering, grading for potential features, and trade-offs. With the outlier product talent density at Anima, there's a heavy focus on coaching and teaching, with no need for line management. We've been able to make huge strides in the NHS because we all deeply understand the problem, grading tasks based on our engineering expertise, and real life clinical trade-offs. This deep domain knowledge is ultimately how we integrated with the major electronic health records (EMIS and SystmOne) in just 4 months, and grew from $150k to $7m in 20 months and 3 product lines. We're relentlessly resourceful. In 14 months, we built an extremely loved enterprise app that users have said 'seems too good to be true'. Anima can take an information complete medical history as good or better than a typical human doctor, and increasingly automates front and back office in a way that would’ve seemed like science fiction a few years ago - for example, Annie (our AI) now deals with a large percentage of documents completely autonomously without a human in the loop. Anima is a safe haven for free thinkers and we've been careful to build a culture where everyone feels comfortable being their complete unfiltered self, sharing their honest thoughts, feelings without ever needing to self-censor. Joining Anima means joining a crew with exceptional talent density, and your crewmates will never let you down. We hire talented people who think from first principles and have high growth potential - great decision makers who deserve to have complete autonomy and are forces of nature when empowered with it. Decisions are never made in isolation by the founders. All information is transparently available to the whole team on our Notion - every meeting, decision, success, failure. We have a live Retool dashboard which shows live MRR, linked to Stripe invoices. We are deeply collaborative, and through mutual and self-challenge, we converge towards the optimum, and decisively execute. We are united by child-like intellectual curiosity and experiment and wander freely when the right path isn’t clear. We believe all future managers should be formidable individual contributors & domain experts. We hire candidates from all over the world. We offer flexibility over work schedule and location. We have a good time! We get the whole team together at least twice a year for team retreats, with the last ones in Brittany (France), La Paz (Mexico), Tuscany (Italy), Dominican Republic! Hi - My name is Shun, a medical doctor and CEO of Anima. Thanks for checking out our job ad! We’re tackling a problem that has affected everyone in some way: Globally, millions die every year because their medical problems aren’t treated quickly enough. Hundreds of millions suffer pain, worry and discomfort needlessly because of long waiting times. We’ve built ambitious software to automate the entire healthcare workflow - from history taking consultations, to report abstraction, to recommending & saving a coded action plan for the patient, ready for a human doctor to greenlight. By doing this, we get patients optimal care within 24 hours and 10x the clinical workflow in the process. It's a win-win for patients and healthcare professionals. We are pretty unique among health techs: we have both medical and engineering domain expertise - there are 4 doctors working full time at Anima, as well as 'pure' software engineers. I wrote the first backend in Node. As a doctor and former HM Treasury health policy advisor managing £4bn budgets in UK health spending, I have full stack domain knowledge and personal experience of the problem we’re solving. Like me, the whole Anima team have personal experience of the problem we're solving: we're building what we wished we had as doctors. Please note that as this role may involve site work and on-site support for our users, we can only consider your application if you are based in the UK. You will not be able to complete our screening task if you are not based in the UK, so please bear this in mind when submitting your application. We hope to welcome you to the team soon! Join Anima, and you'll use your influence and people skills to get Anima into clinics and entire regions: an urgently needed product that saves lives amid critical levels of patient demand, with healthcare systems in crisis across the globe. Since launching in the UK, we're now used in by GP practices, primary care networks and federations across the country who collectively provide care for over 2 million patients. Our current distribution team have said that one of the biggest perks of working at Anima is seeing the delight and disbelief on people’s faces when we show them our demo, something that is truly a 10x generational leap. Here’s what some of our users have been saying: *“I sent a plan to the patient and it’s incredible, within a few minutes they’re coming back to me saying that they can make the appointment!” "I would call that next generation, I think you have that badge" ”Sometimes you need to stop driving a Fiesta and buy a Mercedes"* Lots of us went into medicine because we wanted to maximise our positive impact. At Anima, we understand that distribution is the other half of a legendary product. Here are incredible things we’ve built as a result of our fullstack sales team: A Clinical Director at one of our practices wanted to streamline multiple access channels and make access equitable and fair. After some great discovery and deep listening, the AM together with the customer suggested we build something called ‘proxy requests’, which would allow the reception team at a clinic to complete Anima requests on behalf of a patient who was on a landline call - this made it possible to give someone with no internet or mobile phone the same access to care. This is now one of our most popular features that has led to viral referrals and fanatical users. One of our fullstack account manager, realised that adding a configurable feature that allows patients to self-book appointments directly into the electronic health record calendar would be critical to closing large enterprise accounts. By deeply understanding the pain points and anxieties underlying the feature, Anima built the feature in 9 days, to the great excitement of users at demo calls and $1m+ ACV meetings. Off the back of fanatical referrals from our existing users, the team was invited to present to NHS England at national and regional level, and we’ve been helping to shape the future of the primary care market through an upcoming $1bn+ procurement framework. Hungry and wants their shot to change the world - a force of nature when empowered with the tools, resources and development to do it. Exceptional communicator, able to distill complex information into clear and concise bullets without jargon. An excellent conduit between users and the rest of the company. Able to execute a high sigma discovery process and in combination with incisive people intuition, elucidate deep pain points and opportunities to excite within minutes of the first call. Has incredibly high standards for themselves and an unshakeable growth mindset: able to challenge themselves and those around them to push to do things better. Exceptionally organised: able to build & maintain multiple relationships across a diverse range of organisations, and consistently execute on plans to onboard and retain users. Reliably follows up on 100% of qualified leads at optimal intervals. A gifted relationship builder, able to quickly build rapport and emotional anchors with almost anyone and any persona. Pragmatic rather than dogmatic in decision making: able to weigh real world data appropriately, changing course when necessary towards optimal outcomes for patients and clinicians. Keen to understand the big picture & entire context of the company and vertical; impatient to grow towards a senior executive role. Seeks to maximise combined team productivity, communicating the right things at the right time through the right channels. Intellectually curious and loves learning - able to tackle entirely novel challenges that lack prior precedent through first principles thinking, creatively using the right pragmatic approach, with an understanding of alternatives and trade offs. It's helpful to have B2B/SaaS experience, generating leads of $30-50k+ ACV, but not mandatory - we will make exceptions if you’re a high performing BDR. You need to have demonstrated a high growth mindset and potential for rapid skill development through past projects. For this role, you will need to be based in the UK. We're live with GP teams across the country, being used by teams across the NHS. Over the rest of 2024, we're continuing to onboard teams that want to build the future of healthcare, and will be working with the NHS to deploy Anima at regional & national level. We’ll also be identifying international partners to power Anima’s next stage of growth. We’re looking to add talented account executives who understand the urgency and importance of what we’re doing for society and are hungry to make impact. Our VP Sales has a 90%+ e2e close rate, and the distro org averages about 80%. Our CAC payback, gross margin, retention are all world class and you'll be joining an exceptional team with top metrics for SaaS, despite being in a traditionally slower vertical. First month - some examples of what to expect: Participate in user discovery & demo calls to develop a deep understanding of their fundamental motivations and needs/pain points, translating these insights into optimal feature roadmaps. Source leads and execute campaigns. Get as much exposure as possible to developing the full lifecycle of an opportunity from lead through to closure. Join the team at events & conferences, speaking to potential users, conducting demos and converting leads. Next 6 months - some examples of what to expect: Build domain expertise to scale our prospecting, identifying the teams in the most pain who are likely to become fanatical users of Anima. Become the central point of contact for assigned GP practices and PCNs. Your job is to maximise discounted fanaticism, doing whatever is necessary to help practices start - and continue - using Anima. Work with customer success colleagues to maximise virality and fanaticism across your accounts, doing whatever is needed to ensure every account leads to the maximum number of fanatical referrals. 6+ months - some examples of what to expect: Potential to transition into a Strategic Enterprise AE, with managerial responsibility for junior AEs joining the team. Take on account management responsibility for larger accounts e.g. GP federations and ICSs (covering 1m+ patients). Work with the team to scale our sales & marketing, including working with NHS leaders to identify and secure regional & national-level procurement opportunities, including those beyond primary care.

Every healthcare system in history has been a fundamental trade-off between quality and scale - our mission is to change that. We're building a new category of AI-native healthcare provider, using full-stack care automation to deliver world-class treatment at population scale. Our AI physiotherapy clinic is already democratising access to 24/7 healthcare for NHS patients across the UK, and we're just getting started. Flok is building the new standard for healthcare delivery, loved by patients and partners, and we're growing fast. We're looking for an experienced and ambitious engineering leader to help us expand our capabilities, product range and geographies by building a world-class engineering team. You'll fully take over the management and growth of the team from the CTO, working closely with senior management to ensure that we are capable of achieving our ambitious goals. To excel in this role, you'll have: • A track record of recruiting great engineers, building teams from the ground up, and leading engineering teams of >30. We have a lot of hiring to do, and you'll need to be confident and excited by this. You understand the joys and challenges of building software, and are passionate about growing high performance teams to do it., • Strong systems and first-principles thinking. You'll need to be comfortable in an environment with limited existing processes, and at the same time excited to design new systems to help the team grow and flourish., • Technical background—your engineering instincts and achievements are respected by your peers and you can comfortably discuss advanced computing topics. You'll be completely comfortable reading code in most commonly-used languages, and happy to occasionally get your hands dirty writing production code., • Experience developing software medical devices, either as engineer or manager. A significant part of Flok's software is a medical device, and you'll need to be familiar with the implications for process & structure., • Conviction that LLMs are transforming software engineering for the better, concrete insights of how this could play out, and the ability to convince others. We believe the best companies of the next decade will be those which harness this new power for fun and profit, safely. If you aren't curious and optimistic about AI, you won't fit in here., • Ultimately, a strong bias for action and extreme ownership. We're looking for someone who will take full responsibility for the output of the engineering team and wants to lead a high-performing group of A-players., • Challenging work at the frontier of AI-native healthcare, • In-person collaborative culture in a beautiful work space in the Cambridgeshire countryside, • An onsite gym and digital health subscription of your choice, • Early stage equity with employee-friendly terms (via an EMI scheme), • Comprehensive medical coverage (including dental and optical) and life insurance, • Optional remote working on Wednesdays, with an annual allowance of 10 extra remote days, • Desk setup allowance for your favourite keyboard / mouse / whatever!, • Monthly team feasts (and the BBQ is used most days), • A fast paced work environment geared towards excellence and professional growth (with annual training budget), • A chance to have a big impact in a small team transforming care and outcomes at population scale More than a billion people a year suffer unnecessarily from conditions like MSK pain, where the right treatment approach is well-established but undeliverable at scale. We're changing that. Our team has deep expertise across clinical, engineering, and regulated AI, has a track record of healthtech innovation, and is backed by top VCs and multiple unicorn founder angels. • Solving hard problems at the intersection of technology and healthcare, • The pursuit of excellence—helping each other to do the best work of our careers, • Working in an in-person collaborative environment, • Taking ownership to have significant impact in a fast-growing mission-driven company with big ambitions #J-18808-Ljbffr

Are you a visionary scientist with a passion for oncology and translational research? Do you thrive at the intersection of discovery and clinical development? We are seeking a strategic and scientifically rigorous Translational Medicine Lead to advance programs and drive innovation in our oncology pipeline. This is an exceptional opportunity to join a purpose-driven company and play a foundational role in building translational capabilities that will impact the future of oncology therapies. This is a high-impact individual contributor role with matrix leadership responsibility. This individual collaborates across internal and external stakeholders to integrate translational science into research and clinical development, driving translational research, clinical biomarkers, companion diagnostics, and biomarker-enabled decision making. This position reports to VP Global Translational Medicine as an individual contributor. You can be based in Cambridge, MA, US or Cambridge, UK (Hybrid work according to Orion's policy). • Lead and own Translational Medicine strategy for one or more oncology programs across research to clinical development, with a focus on biomarker development, patient enrichment, companion diagnostics, proof of mechanism and resistance insights., • Subject matter expert in solid tumor biology, disease progression and treatment options; accountable for the strategic design and oversight of implementation of Biomarker strategies associated with disease context and drug modalities., • Serve as the bridge between discovery research and clinical development; providing critical input in developing translational strategies to bring new agents to the clinic., • Ensure translational insights are embedded into study trial design and conduct., • Serve as the single accountable Translational Medicine representative within the Global Project Team., • Partner with internal and external collaborators to deliver clinically validated biomarker assays into clinical studies., • Collaborate closely with CDx lead, translational biology lead, regulatory and commercial to advance companion diagnostic development and regulatory approval., • Deliver timely, high-quality biomarker data and integrated insights to accelerate program decision‐making., • Lead reverse translation via the continuous learning from patients’ data to generate insights that can be back translated to research and early development., • Lead Translational Medicine matrix teams across research, translational pharmacology, clinical development, Bioinformatics, Translational Biology, CDx and QSP., • Ensure the appropriate evaluation of state‑of‑the‑art platform technologies and incorporate innovative biomarkers into translational medicine plans., • Contribute to IND, CTA, and regulatory submissions, ensuring translational strategies support successful approvals., • Ph.D. or equivalent advanced degree in biological sciences or related., • 5+ years relevant translational experience within biotech/pharma., • Strong experience in clinical biomarkers and translational strategy execution., • Experience in oncology drug development., • Proven experience in matrix leadership and cross‑functional delivery., • Deep expertise in cancer biology and treatment landscape., • Deep experience integrating clinical omics data into development decision making., • Hands‑on experience across modalities (e.g., small molecules, ADCs, IO, cell therapies)., • Demonstrated experience with CDx strategy and regulatory pathways., • Strong ability to influence senior stakeholders and drive decisions in a matrix environment., • Ability and willingness to travel internationally as required. #J-18808-Ljbffr

Employer Cambridge University Hospitals NHS Foundation Trust Employer type NHS Site Addenbrooke's Hospital Town Cambridge Salary £113,565 - £150,569 per annum pro-rata Salary period Yearly Closing 06/08/2026 23:59 Interview date 28/08/2026 Applications are invited for the post of Consultant in Acute Medicine (10PAs) at Cambridge University Hospitals NHS Foundation Trust. The successful candidate will be expected to contribute to all aspects of clinical services provided by the Acute Internal Medicine department. AIM clinical services include a GP liaison service, same day emergency care, emergency assessment units and a virtual follow-up clinic. In addition, they are expected to also contribute to teaching and training. The successful candidate will be fully registered with the GMC and have CCT in Acute or General Medicine or be within six months of award of CCT at the time of interview. Applications are welcomed from those unable to work full time for personal reasons or those wishing to job-share. The applicant must have demonstrable skills in listening, reading, writing and speaking in English that enable effective communication about medical topics with patients and colleagues, as set out in the GMC’s Good Medical Practice (2013). Non-UK applicants must possess the IELTS/OET exam before obtaining a GMC licence to practice. Applications from job seekers who require skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website. It is a requirement for skilled worker applicants, applying for entry clearance into the UK, to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) will also be subject to this requirement. Cambridge University Hospitals NHS Foundation Trust is an Equal Opportunities Employer. Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post. You must have appropriate UK professional registration. This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service. Name Dr Akimichi Inaba Job title: Clinical Lead for Acute Internal Medicine Email address: Akimichi.Inaba1@nhs.net Enquiries should be directed to Clinical Lead for Acute Internal Medicine, Dr Akimichi Inaba via email at Akimichi.Inaba1@nhs.net #J-18808-Ljbffr

Job Description Principal Scientist (DMPK) Permanent Cambridge A leading biotech organisation is seeking a Principal Scientist with deep DMPK and quantitative pharmacology expertise to support oncology-focused discovery and early development programmes. You will define and drive translational DMPK strategies across the pipeline, applying mechanistic modelling and pharmacology insight to guide decision‑making from lead optimisation through to IND. Working cross‑functionally, you will play a key role in shaping programme direction and ensuring high‑quality progression of assets toward the clinic. • Define and implement translational DMPK strategies across multiple programmes, from lead optimisation to clinical candidate selection., • Develop and apply PK/PD, PBPK, and other mechanistic models to inform dose, schedule, and exposure‑response relationships., • Integrate in vitro, in vivo, and in silico data to support decision‑making and improve translational confidence., • Partner closely with chemistry, biology, toxicology, and clinical teams to guide programme strategy., • Contribute to human dose prediction and support first‑in‑human study design., • Provide scientific leadership within project teams and across the wider DMPK function., • Oversee external collaborations and CRO activities where required., • Mentor and support development of junior scientists within the team., • Present data and strategic recommendations clearly to internal stakeholders and external collaborators., • PhD (or equivalent experience) in a relevant scientific discipline, with significant industry experience in drug discovery and early development., • Strong expertise in DMPK and quantitative pharmacology, including PK/PD and PBPK modelling., • Experience applying modelling and simulation to support candidate selection and clinical translation., • Familiarity with tools such as Phoenix WinNonlin, NONMEM, MATLAB, or similar., • Proven ability to work in cross‑functional project teams and influence decision‑making., • Experience supporting programmes from discovery through to IND/early clinical development., • Excellent communication skills and the ability to translate complex data into clear insights., • Prior leadership or mentoring experience is desirable. Apply now by attaching your CV in Word, or contact Paige Keenan (paige.keenan@srgtalent.com) for further information about this opportunity. #J-18808-Ljbffr

The National Neurosurgical Audit Programme Fellowship offers a unique opportunity for a Clinical Research Associate Position, enabling a clinical PhD course focused on data curation and analysis, service strategy and quality improvement initiatives. The post-holder will work under the supervision of Professor Adel Helmy and contribute to a programme of research analysing and presenting data on all areas of neurosurgical practice in England’s 24 neurosurgical units, covering approximately 50,000 cases per year. The role also involves participation in the Neurosurgical NHS clinic at Addenbrooke's Hospital. • Completion of general medical training., • Hold MRCP or equivalent qualification., • Registered medical practitioner in the UK, or willingness to work towards registration., • Applicants from any medical specialty and career grade are encouraged. Position duration: 3 years. An honorary clinical contract with the CUH NHS Foundation Trust will be issued, requiring a DBS check. Send enquiries to Professor Adel Helmy at aeh33@cam.ac.uk. Quote reference RR50385 on all correspondence regarding this vacancy. 24th July 2026 The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. #J-18808-Ljbffr

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CSCS Cleaner Required - National Grid, Radlett (WD25 8DT) We are currently looking for an experienced CSCS Cleaner to join a busy construction project at National Grid, Radlett (WD25 8DT).Job Details: ?? Location: National Grid, Radlett, WD25 8DT ?? Rate: £16.Overtime and Saturday work available ??

Early Morning Delivery Drivers Needed!.Join News Team Group, a fast-growing company delivering newspapers and magazines to homes and businesses across the UK.Were looking for reliable, self-employed delivery drivers who are ready to hit the road and make an impact in their local community.Join a tea

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