Postdoctoral Researcher - Biodiversity Cell Atlas Database
3 days ago
Barcelona
ph3Postdoctoral Researcher - Biodiversity Cell Atlas Database /h3 pThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies. /p pThe CRG is recruiting a computational biologist with advanced experience in single-cell data analysis. The position will entail processing of novel and existing single-cell transcriptomic datasets from diverse species across the tree of life, combining comparative genomics, functional gene annotation, and cross-species comparisons to biologically interpret diverse datasets that will be hosted in the BCA database. The candidate will be a part of a highly interdisciplinary team that includes computational, evolutionary and molecular biologists in different groups at CRG (including the Bioinformatics Unit), and this project will be developed jointly with EBI and the Wellcome Sanger Institute. /p pCells are the fundamental units of life – underlying cooperative functions in multicellular organisms and complex temporal life cycles in microbial eukaryotes. In recent years, the rapid advance in single-cell genomics technologies, combined with the growing availability of whole-genome sequences, opened up the opportunity to systematically map cell types in diverse organisms. /p pThe goal of the Biodiversity Cell Atlas is to articulate a community effort to build whole-organism cell atlases across the diversity of life, working in a phylogenetically informed way, supported by high-quality genomes, and using shared standards that make comparisons across diversity possible. This coordinated effort should boost our understanding the evolution and diversity of life at cellular resolution: from gene regulatory programs, through cell type molecular profiles, to biological interactions between species. /p pAt CRG, and together with EBI, we are developing the computational infrastructure to host a multi-species database for the Biodiversity Cell Atlas initiative. This will enable the interactive exploration of cell type molecular maps, gene co-expression profiles across evolution, comparison of cell types across species, and more. /p ul liAdvanced experience in single-cell data analysis and interpretation /li liExperience in deep learning methods for single-cell data integration /li liProficiency in Python, R, and Linux /li /ul h3Desirable but not required /h3 ul liExperience working with functional genomics data in non-model species /li /ul h3Education and training /h3 ul liA PhD in Bioinformatics, Biology, or related disciplines /li /ul h3Languages /h3 ul liYou are fluent in English /li /ul h3Technical skills /h3 ul liHands‑on single‑cell data processing and downstream analysis (clustering, visualization, annotation, etc.) /li liCapacity to integrate diverse genomics sources (gene annotations, phylogenetic analyses, protein structures, etc.) to support the biological interpretation of single‑cell data /li /ul h3Competences /h3 ul liHighly developed organization and coordination skills /li liDedication, motivation, and rigor in scientific pursuits /li liCapacity to work both independently and as part of a team /li /ul h3The Offer – Working Conditions /h3 ul libContract duration: /b Technical and scientific activities contract linked to the duration of the project (estimated 18 months). /li libEstimated annual gross salary: /b Salary is commensurate with qualifications and consistent with our pay scales. /li /ul pWe provide a highly stimulating environment with state‑of‑the‑art infrastructures, and unique professional career development opportunities. /p pWe offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity. /p pThe CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours. /p /p #J-18808-Ljbffr
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